Omega-3 fatty acids: their beneficial role in cardiovascular health
- PMID: 16812965
- PMCID: PMC1780156
Omega-3 fatty acids: their beneficial role in cardiovascular health
Erratum in
- Can Fam Physician. 2006 Aug;52:952
Abstract
Objective: To examine evidence for the role of omega-3 fatty acids in cardiovascular disease.
Quality of evidence: PubMed was searched for articles on the role of omega-3 fatty acids in cardiovascular disease. Level I and II evidence indicates that omega-3 fatty acids are beneficial in improving cardiovascular outcomes.
Main message: Dietary intake of omega-3 fatty acids has declined by 80% during the last 100 years, while intake of omega-6 fatty acids has greatly increased. Omega-3 fatty acids are cardioprotective mainly due to beneficial effects on arrhythmias, atherosclerosis, inflammation, and thrombosis. There is also evidence that they improve endothelial function, lower blood pressure, and significantly lower triglycerides.
Conclusion: There is good evidence in the literature that increasing intake of omega-3 fatty acids improves cardiac outcomes. Physicians need to integrate dietary recommendations for consumption of omega-3 fatty acids into their usual cardiovascular care.
OBJECTIF: Relever les données sur le rôle des acides gras oméga-3 dans les maladies cardiovasculaires.
QUALITÉ DES PREUVES: On a consulté PubMed, à la recherche d’articles sur le rôle des oméga-3 dans les maladies cardiovasculaires. Il existe des preuves de niveaux I et II indiquant que les oméga-3 ont un effet favorable sur les issues cardiovasculaires.
PRINCIPAL MESSAGE: Au cours des 100 dernières années, la consommation des acides gras oméga-3 a diminué de 80%, pendant que celle des oméga-6 augmentait considérablement. Les oméga-3 sont cardioprotecteurs en raison surtout de leurs effets bénéfiques sur les arythmies, l’athérosclérose, l’inflammation et la thrombose. Selon certaines données, ils améliorent aussi l’activité endothéliale, diminuent la tension artérielle et causent une baisse significative des triglycérides.
CONCLUSION: Il existe dans la littérature des preuves convaincantes indiquant qu’une consommation accrue d’acides gras oméga-3 améliore les issues cardiaques. Le médecin devrait incorporer aux soins cardiovasculaires habituels des recommandations pour encourager la consommation des oméga-3.
Conflict of interest statement
Competing interests: None declared
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Comment in
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Promoting ALA as a source of omega-3.Can Fam Physician. 2006 Oct;52(10):1205; author reply 1205-6. Can Fam Physician. 2006. PMID: 17279173 Free PMC article. No abstract available.
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Clarifying omega-3 fatty acid recommendations.Can Fam Physician. 2006 Sep;52(9):1060-1; author reply 1061-2. Can Fam Physician. 2006. PMID: 17279211 Free PMC article. No abstract available.
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Clarifying omega-3 fatty acid recommendations.Can Fam Physician. 2006 Sep;52(9):1061; author reply 1061-2. Can Fam Physician. 2006. PMID: 17279212 Free PMC article. No abstract available.
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