Gene amplification: yeast takes a turn
- PMID: 16814711
- DOI: 10.1016/j.cell.2006.06.012
Gene amplification: yeast takes a turn
Abstract
The origins of gene amplifications in mammalian cells have been difficult to analyze because of secondary genome rearrangements. Recent studies in budding yeast, including in this issue of Cell, have provided new insights into the role of palindromic sequences in gene amplification.
Comment on
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The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks.Cell. 2006 Jun 30;125(7):1283-96. doi: 10.1016/j.cell.2006.04.042. Cell. 2006. PMID: 16814715
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