Designer macrophages: oxidative metabolism fuels inflammation repair
- PMID: 16814727
- DOI: 10.1016/j.cmet.2006.06.001
Designer macrophages: oxidative metabolism fuels inflammation repair
Abstract
Macrophages play a central role in immunity, contributing to both the initiation and resolution of inflammation. In this issue of Cell Metabolism, Vats et al. provide insight into the mechanisms by which reparative macrophages are generated and reveal a previously unappreciated link between this anti-inflammatory axis and mitochondrial oxidative metabolism (Vats el al., 2006).
Comment on
-
Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation.Cell Metab. 2006 Jul;4(1):13-24. doi: 10.1016/j.cmet.2006.05.011. Cell Metab. 2006. PMID: 16814729 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
