[Laboratory diagnoses of the first confirmed human case of avian influenza A (H5N1) in the mainland of China]
- PMID: 16816853
[Laboratory diagnoses of the first confirmed human case of avian influenza A (H5N1) in the mainland of China]
Abstract
Background: To determine the etiologic agent of an atypical pneumonia human case admitted to Xiangtan City hospital, Hunan Province in Oct. 2005.
Methods: The patient's respiratory tract samples and serum were collected. Throat swabs were tested by microneutralization and hemagglutination-inhibition assays.
Results: The results of nucleic acid detection of all respiratory samples were negative and virus isolation was also negative. The H5-specific antibodies of convalescence showed a 4-fold greater rise than acute phase.
Conclusion: The atypical pneumonias case was confirmed as the first human case of avian influenza A (H5N1) infection in the mainland of China.
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