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Review
. 2006;45(11):733-7.
doi: 10.2169/internalmedicine.45.1671. Epub 2006 Jul 3.

De novo CD5-positive diffuse large B-cell lymphoma of the temporal bone presenting with an external auditory canal tumor

Shoko Ogawa  1 , Isao Tawara, Satoshi Ueno, Miho Kimura, Kana Miyazaki, Hiroyoshi Nishikawa, Motoko Yamaguchi, Tohru Kobayashi, Hiroshi Shiku
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Free article
Review

De novo CD5-positive diffuse large B-cell lymphoma of the temporal bone presenting with an external auditory canal tumor

Shoko Ogawa et al. Intern Med. 2006.
Free article

Abstract

We report a 74-year-old woman with primary CD5-positive diffuse large B-cell lymphoma (DLBCL) of the temporal bone. The patient was admitted because of a mass in the left external auditory canal. She was treated with eight courses of CEOP therapy (rituximab was added from the sixth course) followed by radiotherapy of 40 Gy, and complete remission was achieved. The occurrence of malignant lymphoma in the temporal bone, which is an extremely unusual site, may have depended on the peculiarity of CD5-positive DLBCL.

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