doi: 10.1142/s0219720006001837.
Analysis of conserved hydrophobic cores in proteins and supramolecular complexes
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- PMID: 16819788
- DOI: 10.1142/s0219720006001837
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Analysis of conserved hydrophobic cores in proteins and supramolecular complexes
J Bioinform Comput Biol.
2006 Apr.
Abstract
The conserved hydrophobic core is an important feature of a family of protein domains. We suggest a procedure for finding and the analysis of conserved hydrophobic cores. The procedure is based on using an original program called CluD (http://monkey.belozersky.msu.ru/CluD/cgi-bin/hftri.pl). Conserved hydrophobic cores of several families including homeodomains and interlock-containing domains are described. Hydrophobic clusters on some protein-DNA and protein-protein interfaces were also analyzed.
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