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Comment
. 2006:2:39.
doi: 10.1038/msb4100079. Epub 2006 Jul 4.

Microarraying the cellular microenvironment

Jae-Hyung Jang, David V Schaffer
Comment

Microarraying the cellular microenvironment

Jae-Hyung Jang et al. Mol Syst Biol. 2006.
No abstract available

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Figures

Figure 1
Figure 1
Schematic representation of a microenvironment array. Combinations of signals and adhesion molecules are printed onto an aldehyde-activated surface to generate an array of 350–500 μm diameter spots. Suspended cells are briefly incubated on the array and single-cell populations are captured on the spots by adherence to the printed extracellular matrix components or adhesion molecules. Automated fluorescence microscopy and computer-assisted feature extraction allows a high-throughput quantitative analysis of multiple phenotypic outcomes at the single cell level.
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