Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 Oct 1;72(1):9-17.
doi: 10.1016/j.cardiores.2006.06.004. Epub 2006 Jun 6.

Vascular smooth muscle cell senescence in atherosclerosis

Isabelle Gorenne  1 , Mary Kavurma, Stephen Scott, Martin Bennett
Affiliations
Review

Vascular smooth muscle cell senescence in atherosclerosis

Isabelle Gorenne et al. Cardiovasc Res. .

Abstract

Markers of cell senescence have been identified in both the blood and vessel wall of patients with atherosclerosis. In particular, vascular smooth muscle cells (VSMCs) derived from human plaques show numerous features of senescence both in culture and in vivo. This review summarises the evidence for VSMC senescence in atherosclerosis, and outlines the mechanisms and triggers leading to their senescence.

PubMed Disclaimer

Substances

LinkOut - more resources