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Review
. 2006 Jul:44 Spec No:S24-40.
doi: 10.1002/mrc.1816.

Solution NMR of membrane proteins: practice and challenges

Charles R Sanders  1 , Frank Sönnichsen
Affiliations
Review

Solution NMR of membrane proteins: practice and challenges

Charles R Sanders et al. Magn Reson Chem. 2006 Jul.

Abstract

This review focuses upon the application of solution NMR methods to multispan integral membrane proteins, particularly with respect to determination of global folds by this approach. Practical methods are described along with the special difficulties that confront the application of solution NMR to proteins that dwell in the netherworld of the lipid bilayer.

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