Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Aug;64(4):249-54.
doi: 10.1080/00016350600633243.

Xerostomia and medications among 32-year-olds

William Murray Thomson  1 , Richie Poulton, Jonathan Mark Broadbent, Shaima Al-Kubaisy
Affiliations

Xerostomia and medications among 32-year-olds

William Murray Thomson et al. Acta Odontol Scand. 2006 Aug.

Abstract

Objective: To describe the prevalence and associations of xerostomia among adults in their early thirties, with particular attention to medication exposure as a putative risk factor.

Material and methods: The prevalence and associations of xerostomia were investigated among 32-year-old participants in a long-standing prospective cohort study. Some 950 individuals were assessed at ages 26 and 32 years, with medications being recorded on both occasions.

Results: The prevalence of xerostomia was 10.0% (with no apparent gender difference), and was significantly higher among those taking antidepressants (odds ratio = 4.7), iron supplements (OR = 4.1) or narcotic analgesics (OR = 2.4). Those taking antidepressants at both ages 26 and 32 years had 22 times the odds of reporting xerostomia.

Conclusion: Xerostomia may be a problem for a sizeable minority of young adults.

PubMed Disclaimer

Figures

Figure 1
Figure 1
CHAID tree patterns for xerostomia (in each cell, the percentage who were xerostomic is given in parentheses).
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Fox PC, Busch KA, Baum BJ. Subjective reports of xerostomia and objective measures of salivary gland performance. J Am Dent Assoc. 1987;115:581–4. - PubMed
    1. Locker D. Dental status, xerostomia and the oral health-related quality of life of an elderly institutionalized population. Spec Care Dentist. 2003;23:86–93. - PubMed
    1. Cassolato SF, Turnbull RS. Xerostomia: clinical aspects and treatment. Gerodontology. 2003;20:64–77. - PubMed
    1. Thomson WM. Issues in the epidemiological investigation of dry mouth. Gerodontology. 2005;22:65–76. - PubMed
    1. Nederfors T, Isaksson R, Mörnstad H, Dahlöf C. Prevalence of perceived symptoms of dry mouth in an adult Swedish population: relation to age, sex and pharmacotherapy. Community Dent Oral Epidemiol. 1997;25:211–6. - PubMed

Publication types