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Review
. 2006 Jul 10;24(20):3293-8.
doi: 10.1200/JCO.2006.06.8080.

Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker

Nola Hylton  1
Affiliations
Review

Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker

Nola Hylton. J Clin Oncol. .

Abstract

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is being used in oncology as a noninvasive method for measuring properties of the tumor microvasculature. There is potential for DCE-MRI to be used as an imaging biomarker to measure antiangiogenic effects of cancer treatments. This article reviews the general methodology for performing DCE-MRI and discusses existing data and challenges to applying DCE-MRI for treatment response assessment in clinical trials.

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