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Review
. 2006 Jul;102(1):35-9.
doi: 10.1016/j.tripleo.2005.12.023. Epub 2006 Apr 24.

The PFAPA syndrome in oral medicine: differential diagnosis and treatment

Andres Pinto  1 , Rochelle G Lindemeyer, Thomas P Sollecito
Affiliations
Review

The PFAPA syndrome in oral medicine: differential diagnosis and treatment

Andres Pinto et al. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Jul.

Abstract

Periodic fever syndromes in children can present with orofacial manifestations which contribute to the formulation of a differential diagnosis. Because of the early onset of oral lesions in these syndromes, the oral medicine practitioner may be required to assist in their diagnosis and management. The periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome has been classified as a type of periodic fever syndrome ocurring in early childhood. This article presents a review of the published literature on this entity and summarizes current therapeutic options.

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Comment in

  • Thalidomide for treatment of PFAPA syndrome.
    Marque M, Guillot B, Bessis D. Marque M, et al. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Mar;103(3):306-7; author reply 307. doi: 10.1016/j.tripleo.2006.10.011. Epub 2006 Dec 19. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007. PMID: 17182263 No abstract available.

MeSH terms