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. 2006 Jul 19;128(28):9042-3.
doi: 10.1021/ja062025p.

Speeding up three-dimensional protein NMR experiments to a few minutes

Paul Schanda  1 , Hélène Van Melckebeke, Bernhard Brutscher
Affiliations

Speeding up three-dimensional protein NMR experiments to a few minutes

Paul Schanda et al. J Am Chem Soc. .

Abstract

We demonstrate for different protein samples that three-dimensional HNCO and HNCA correlation spectra may be recorded in a few minutes acquisition time using the band-selective excitation short-transient sequences presented here. This opens new perspectives for the NMR structural investigation of unstable protein samples and real-time site-resolved studies of protein kinetics.

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