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. 2006 Jul;6(7):1307-10.
doi: 10.1021/nl0610836.

Infrared spectroscopic mapping of single nanoparticles and viruses at nanoscale resolution

Markus Brehm  1 , Thomas Taubner, Rainer Hillenbrand, Fritz Keilmann
Affiliations

Infrared spectroscopic mapping of single nanoparticles and viruses at nanoscale resolution

Markus Brehm et al. Nano Lett. 2006 Jul.

Abstract

We demonstrate that scattering near-field microscopy (s-SNOM) can determine infrared "fingerprint" spectra of individual poly(methyl methacrylate) nanobeads and viruses as small as 18 nm. Amplitude and phase spectra are found surprisingly strong, even at a probed volume of only 10(-20) l, and robust in regard to particle size and substrate. This makes infrared spectroscopic s-SNOM a versatile tool for chemical and-in the case of protein-secondary-structure identification.

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