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. 2006 Jul;12(7):1149-52.
doi: 10.3201/eid1207.051558.

Azithromycin failure in Mycoplasma genitalium urethritis

Catriona S Bradshaw  1 , Jorgen S Jensen, Sepehr N Tabrizi, Timothy R H Read, Suzanne M Garland, Carol A Hopkins, Lorna M Moss, Christopher K Fairley
Affiliations

Azithromycin failure in Mycoplasma genitalium urethritis

Catriona S Bradshaw et al. Emerg Infect Dis. 2006 Jul.

Abstract

We report significant failure rates (28%, 95% confidence interval 15%-45%) after administering 1 g azithromycin to men with Mycoplasma genitalium-positive nongonococcal urethritis. In vitro evidence supported reduced susceptibility of M. genitalium to macrolides. Moxifloxacin administration resulted in rapid symptom resolution and eradication of infection in all cases. These findings have implications for management of urethritis.

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