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Review
. 2006 Jul;64(7):1333-7.

[HIV infection]

[Article in Japanese]
Affiliations
  • PMID: 16838653
Review

[HIV infection]

[Article in Japanese]
Natsuo Tachikawa. Nihon Rinsho. 2006 Jul.

Abstract

HIV infection can cause the destruction of cellular immunity. Highly active antiretroviral therapy (HAART) has strong effects to HIV-1 and usually consists of three to four anti-HIV-1 drugs. HAART has caused dramatic change of prognoses in HIV-1 patients. But HAART has several problems to be overcome. IFN-alpha/beta also has anti-HIV-1 effects and single usage of IFN can cause reduction of plasma HIV RNA viral load with about 1 log10 copies/ml after two to eight weeks. IFN can function as an additional anti-HIV-1 drug experimentally, especially to primary or early phase patients and patients with multiple drug resistances.

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