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Review
. 2006 Jul 14;126(1):19-22.
doi: 10.1016/j.cell.2006.06.024.

Flipping riboswitches

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Free article
Review

Flipping riboswitches

Evgeny Nudler. Cell. .
Free article

Abstract

Riboswitches are common cis-acting regulatory elements in bacteria. They are made of nascent RNA that changes its conformation in response to direct binding of cognate metabolites. The publication of five high-resolution crystal structures provides a comprehensive view of how riboswitches sense their ligands and points to new challenges in this emerging field.

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