Review
doi: 10.1016/j.cell.2006.06.026.
Heterotrimeric G protein signaling: Getting inside the cell
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- PMID: 16839871
- DOI: 10.1016/j.cell.2006.06.026
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Review
Heterotrimeric G protein signaling: Getting inside the cell
Cell.
.
Free article
Abstract
Heterotrimeric G proteins have traditionally been thought to transduce signals at the plasma membrane. In this issue, Slessareva et al. (2006) now show that a G protein alpha subunit acts at the endosome to stimulate a phosphatidylinositol 3-kinase to help yeast respond to mating pheromones.
Comment on
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Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome.Cell. 2006 Jul 14;126(1):191-203. doi: 10.1016/j.cell.2006.04.045. Cell. 2006. PMID: 16839886
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