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. 1975 Aug;16(2):250-8.
doi: 10.1128/JVI.16.2.250-258.1975.

Intracellular synthesis of mouse mammary tumor virus polypeptides: indication of a precursor glycoprotein

C Dickson, J P Puma, S Nandi

Intracellular synthesis of mouse mammary tumor virus polypeptides: indication of a precursor glycoprotein

C Dickson et al. J Virol. 1975 Aug.

Abstract

Mouse mammary tumor virus polypeptides were detected in the cytoplasm of mouse mammary tumor cell cultures using immunological precipitation techniques. The anti-mouse mammary tumor virus serum precipitated the major virion glycoproteins gp49 and gp37.5/33.5 and a viral-related nonvirion glycoprotein of 76,000 daltons. Subcellular fractionation studies revelaed that the cell-associated virion glycoproteins were present in the membrane fraction. Pulsechase experiments indicated that a viral-related nonvirion glycoprotein of 76,000 daltons may be a precursor to one or more of the virion glycoproteins.

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