Effect of omega-conotoxin GVIA on neurotransmitter release at the mouse neuromuscular junction
- PMID: 1684129
- DOI: 10.1016/0006-8993(91)90156-p
Effect of omega-conotoxin GVIA on neurotransmitter release at the mouse neuromuscular junction
Abstract
The effect of omega-conotoxin GVIA (omega-CgTx) was studied on spontaneous, K(+)-induced and electrically evoked neurotransmitter release at the neuromuscular junction of mouse diaphragm. omega-CgTx decreased the frequency and amplitude of basal and K(+)-induced miniature end plate potentials. This effect was abolished by raising the extracellular Ca2+ concentration. omega-CgTx had no effect on the quantal content of the electrically evoked release in this preparation.
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