Recent developments in the clinical pharmacology of classical cytotoxic chemotherapy
- PMID: 16842376
- PMCID: PMC1885069
- DOI: 10.1111/j.1365-2125.2006.02714.x
Recent developments in the clinical pharmacology of classical cytotoxic chemotherapy
Abstract
Advances in analytical methods, imaging techniques and an increased understanding of the influence of pharmacogenetic factors have added to our knowledge of the pharmacology of many chemotherapeutic agents. Extending the use of these approaches to pharmacodynamic end-points, together with the application of population-based modelling techniques, offers the potential to develop truly individualized therapy in the future.
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