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. 1975 Jul;70(1):147-51.

Oat cell carcinoma as a malignant apudoma

L H Smith
  • PMID: 168443

Oat cell carcinoma as a malignant apudoma

L H Smith. J Thorac Cardiovasc Surg. 1975 Jul.

Abstract

The neural crest origin of cells secreting amine and polypeptide hormones (APUD cells) is a unifying concept. The relationship of the classical endocrine system to that of tumor hormone secretion can be explained by the diffuse migration and later neoplasia of these unique cells. This paper describes the APUD cell origins of oat cell carcinoma.

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