BABELOMICS: a systems biology perspective in the functional annotation of genome-scale experiments
- PMID: 16845052
- PMCID: PMC1538844
- DOI: 10.1093/nar/gkl172
BABELOMICS: a systems biology perspective in the functional annotation of genome-scale experiments
Abstract
We present a new version of Babelomics, a complete suite of web tools for functional analysis of genome-scale experiments, with new and improved tools. New functionally relevant terms have been included such as CisRed motifs or bioentities obtained by text-mining procedures. An improved indexing has considerably speeded up several of the modules. An improved version of the FatiScan method for studying the coordinate behaviour of groups of functionally related genes is presented, along with a similar tool, the Gene Set Enrichment Analysis. Babelomics is now more oriented to test systems biology inspired hypotheses. Babelomics can be found at http://www.babelomics.org.
References
-
- Stelzl U., Worm U., Lalowski M., Haenig C., Brembeck F.H., Goehler H., Stroedicke M., Zenkner M., Schoenherr A., Koeppen S., et al. A human protein–protein interaction network: a resource for annotating the proteome. Cell. 2005;122:957–968. - PubMed
-
- Rual J.F., Venkatesan K., Hao T., Hirozane-Kishikawa T., Dricot A., Li N., Berriz G.F., Gibbons F.D., Dreze M., Ayivi-Guedehoussou N., et al. Towards a proteome-scale map of the human protein–protein interaction network. Nature. 2005;437:1173–1178. - PubMed
-
- Hallikas O., Palin K., Sinjushina N., Rautiainen R., Partanen J., Ukkonen E., Taipale J. Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity. Cell. 2006;124:47–59. - PubMed
-
- Stuart J.M., Segal E., Koller D., Kim S.K. A gene-coexpression network for global discovery of conserved genetic modules. Science. 2003;302:249–255. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
