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Review
. 2006 Aug;7(8):632-44.
doi: 10.1038/nrg1901.

Highly parallel genomic assays

Jian-Bing Fan  1 , Mark S Chee, Kevin L Gunderson
Affiliations
Review

Highly parallel genomic assays

Jian-Bing Fan et al. Nat Rev Genet. 2006 Aug.

Abstract

Recent developments in highly parallel genome-wide assays are transforming the study of human health and disease. High-resolution whole-genome association studies of complex diseases are finally being undertaken after much hypothesizing about their merit for finding disease loci. The availability of inexpensive high-density SNP-genotyping arrays has made this feasible. Cancer biology will also be transformed by high-resolution genomic and epigenomic analysis. In the future, most cancers might be staged by high-resolution molecular profiling rather than by gross cytological analysis. Here, we describe the key developments that enable highly parallel genomic assays.

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