doi: 10.1038/nrg1917.
The chromosome number in humans: a brief history
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- PMID: 16847465
- DOI: 10.1038/nrg1917
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The chromosome number in humans: a brief history
Nat Rev Genet.
2006 Aug.
Abstract
Following the rediscovery of Mendel's work in 1900, the field of genetics advanced rapidly. Human genetics, however, lagged behind; this was especially noticeable in cytogenetics, which was already a mature discipline in experimental forms in the 1950s. We did not know the correct human chromosome number in 1955, let alone were we able to detect a chromosomal abnormality. In 1956 a discovery was reported that markedly altered human cytogenetics and genetics. The following is an analysis of that discovery.
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