Shape variation of bilayer membrane daughter vesicles induced by anisotropic membrane inclusions
- PMID: 16847752
- PMCID: PMC6275760
- DOI: 10.2478/s11658-006-0009-3
Shape variation of bilayer membrane daughter vesicles induced by anisotropic membrane inclusions
Abstract
A theoretical model of a two-component bilayer membrane was used in order to describe the influence of anisotropic membrane inclusions on shapes of membrane daughter micro and nano vesicles. It was shown that for weakly anisotropic inclusions the stable vesicle shapes are only slightly out-of-round. In contrast, for strongly anisotropic inclusions the stable vesicle shapes may significantly differ from spheres, i.e. they have a flattened oblate shape at small numbers of inclusions in the membrane, and an elongated cigar-like prolate shape at high numbers of inclusions in the vesicle membrane.
Similar articles
-
Coupling between vesicle shape and lateral distribution of mobile membrane inclusions.Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Apr;73(4 Pt 1):041915. doi: 10.1103/PhysRevE.73.041915. Epub 2006 Apr 13. Phys Rev E Stat Nonlin Soft Matter Phys. 2006. PMID: 16711844
-
Vesicle shape, molecular tilt, and the suppression of necks.Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Sep;76(3 Pt 1):031908. doi: 10.1103/PhysRevE.76.031908. Epub 2007 Sep 11. Phys Rev E Stat Nonlin Soft Matter Phys. 2007. PMID: 17930272
-
The many-body problem for anisotropic membrane inclusions and the self-assembly of "saddle" defects into an "egg carton".Biophys J. 2002 Dec;83(6):2898-905. doi: 10.1016/S0006-3495(02)75299-5. Biophys J. 2002. PMID: 12496066 Free PMC article.
-
Roles of bilayer material properties in function and distribution of membrane proteins.Annu Rev Biophys Biomol Struct. 2006;35:177-98. doi: 10.1146/annurev.biophys.35.040405.102022. Annu Rev Biophys Biomol Struct. 2006. PMID: 16689633 Review.
-
Shape behavior of lipid vesicles as the basis of some cellular processes.Anat Rec. 2002 Nov 1;268(3):215-25. doi: 10.1002/ar.10156. Anat Rec. 2002. PMID: 12382320 Review.
Cited by
-
Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane.Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15340-5. doi: 10.1073/pnas.0804746105. Epub 2008 Sep 30. Proc Natl Acad Sci U S A. 2008. PMID: 18829441 Free PMC article.
-
Modulation of the pHLIP transmembrane helix insertion pathway.Biophys J. 2012 Apr 18;102(8):1846-55. doi: 10.1016/j.bpj.2012.03.021. Biophys J. 2012. PMID: 22768940 Free PMC article.
-
Bilayer interactions of pHLIP, a peptide that can deliver drugs and target tumors.Biophys J. 2008 Jul;95(1):225-35. doi: 10.1529/biophysj.107.124156. Epub 2008 Mar 21. Biophys J. 2008. PMID: 18359793 Free PMC article.
-
Mesoscale computational studies of membrane bilayer remodeling by curvature-inducing proteins.Phys Rep. 2014 Oct 1;543(1):1-60. doi: 10.1016/j.physrep.2014.05.001. Phys Rep. 2014. PMID: 25484487 Free PMC article.
-
Systems biology and physical biology of clathrin-mediated endocytosis.Integr Biol (Camb). 2011 Aug;3(8):803-15. doi: 10.1039/c1ib00036e. Epub 2011 Jul 26. Integr Biol (Camb). 2011. PMID: 21792431 Free PMC article. Review.
References
-
- Singer S.J., Nicholson G.L. The fluid mosaic model of the structure of cell membranes. Science. 1972;175:720–731. - PubMed
-
- Israelachvili J.N. Intermolecular and surface forces. London: Academic Press Limited; 1997.
-
- Fisicaro E. Gemini surfactants: Chemico-physical and biological properties. Cell. Mol. Biol. Lett. 1997;2:45–63.
-
- Helfrich W. Elastic properties of lipid bilayers: Theory and possible experiments. Z. Naturforsch. 1973;28:693–703. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources