Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 Aug;55(8):1065-7.
doi: 10.1136/gut.2005.086348.

How do SSRIs help patients with irritable bowel syndrome?

F Creed  1
Affiliations
Review

How do SSRIs help patients with irritable bowel syndrome?

F Creed. Gut. 2006 Aug.

Abstract

Selective serotonin reuptake inhibitor antidepressants seem to promote global well being in some patients with irritable bowel syndrome and, possibly, some improvement in abdominal pain and bowel symptoms, but this effect appears to be independent of improved depression

PubMed Disclaimer

Comment on

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Tack J, Broekaert D, Fischler B.et al A controlled crossover study of the selective serotonin reuptake inhibitor citalopram in irritable bowel syndrome. Gut 2006551095–1103. - PMC - PubMed
    1. Drossman D A, Creed F H, Olden K W.et al Psychosocial aspects of the functional gastrointestinal disorders. In: Drossman DA, Corazziari E, Talley NJ, et al, eds. Rome II. The functional gastrointestinal disorders: Diagnosis, pathophysiology and treatment; A multinational consensus, 2nd Edn. Virginia: Degnon and Associates, 2000157–245.
    1. Jackson J L, O'Malley P G, Tomkins G.et al Treatment of functional gastrointestinal disorders with anti‐depressants: A meta‐analysis. Am J Med 200010865–72. - PubMed
    1. Tabas G, Beaves M, Wang J.et al Paroxetine to treat irritable bowel syndrome not responding to high‐fiber diet: a double‐blind, placebo‐controlled trial. Am J Gastroenterol 200499914–920. - PubMed
    1. Kuiken S D, Tytgat G N, Boeckxstaens G E. The selective serotonin reuptake inhibitor fluoxetine does not change rectal sensitivity and symptoms in patients with irritable bowel syndrome: a double blind, randomized, placebo‐controlled study. Clin Gastroenterol Hepatol 20031219–228. - PubMed

MeSH terms

Substances