Significance of anti-inflammatory effects of PPARgamma agonists?
- PMID: 16849341
- PMCID: PMC1856254
- DOI: 10.1136/gut.2005.089946
Significance of anti-inflammatory effects of PPARgamma agonists?
Abstract
Peroxisome proliferator activated receptor γ expression in mucosal epithelial cells seems to be crucial for its anti‐inflammatory effects with respect to experimental colitis, and for maintaining homeostasis of the mucosal barrier, at least in animal models
Conflict of interest statement
Conflict of interest: None declared.
Comment on
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Peroxisome proliferator activated receptor gamma in colonic epithelial cells protects against experimental inflammatory bowel disease.Gut. 2006 Aug;55(8):1104-13. doi: 10.1136/gut.2005.081745. Epub 2006 Mar 17. Gut. 2006. PMID: 16547072 Free PMC article.
References
-
- Kersten S, Desvergne B, Wahli W. Roles of PPARs in health and disease. Nature 2000405421–424. - PubMed
-
- Berger J, Moller D E. The mechanisms of action of PPARs. Annu Rev Med 200253409–435. - PubMed
-
- Escher P, Wahli W. Peroxisome proliferator‐activated receptors: insight into multiple cellular functions. Mutat Res 2000448121–138. - PubMed
-
- Michalik L, Wahli W. Peroxisome proliferator‐activated receptors: three isotypes for a multitude of functions. Curr Opin Biotechnol 199910564–570. - PubMed
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