Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 Oct;32(4):655-65.
doi: 10.1093/schbul/sbl009. Epub 2006 Jul 18.

Enhancing validity in co-occurring disorders treatment research

Affiliations
Review

Enhancing validity in co-occurring disorders treatment research

Gregory J McHugo et al. Schizophr Bull. 2006 Oct.

Abstract

Despite the high prevalence of co-occurring mental health and substance-use disorders, there has been a relative lack of treatment research with this population, and the existing research often has limited validity. This article explores some of the barriers to the conduct of research on promising interventions for substance-abuse treatment for people with co-occurring disorders, using the concepts of external and ecological validity to make recommendations for future investigation. The central recommendation is to move rapidly from efficacy studies to more credible and valid effectiveness studies, in order to facilitate the adoption of evidence-based interventions in routine practice settings.

PubMed Disclaimer

Comment in

References

    1. New Freedom Commission on Mental Health. Achieving the Promise: Transforming Mental Health Care in America. Rockville, Md. DHHS Publication No. SMA-03–3831; 2003.
    1. Drake RE, Brunette MF. Complications of severe mental illness related to alcohol and other drug use disorders. In: Galanter M, editor. Recent Developments in Alcoholism. Volume XIV, Consequences of Alcoholism. New York: Plenum; 1998. pp. 285–299. - PubMed
    1. Caton CLM, Drake RE, Hasin D, et al. Differences between early phase primary psychotic disorders with concurrent substance use and substance-induced psychoses. Arch Gen Psychiatry. 2005;62:137–145. - PubMed
    1. Petrakis IL, Nich CI, Ralevski E. Schizophrenia and alcohol abuse: a review of pharmacotherapeutic strategies and a report on the effectiveness of naltrexone and disulfiram. Schizophr Bull. In press. - PMC - PubMed
    1. Lehman AF, Herron JD, Schwartz RP, Myers CP. Rehabilitation for young adults with severe mental illness and substance use disorders: a clinical trial. J Nerv Ment Dis. 1993;181:86–90. - PubMed

Publication types

MeSH terms