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. 2006 Jul 19:1:17.
doi: 10.1186/1745-6673-1-17.

Dermal absorption of aromatic amines in workers with different skin lesions: a report on 4 cases

Gintautas Korinth  1 , Tobias Weiss, Jürgen Angerer, Hans Drexler
Affiliations

Dermal absorption of aromatic amines in workers with different skin lesions: a report on 4 cases

Gintautas Korinth et al. J Occup Med Toxicol. .

Abstract

There are only few studies about the relationship of skin lesions and the percutaneous uptake of hazardous substances in exposed workers. Several aromatic amines are well known carcinogens for humans and/or animals. This case report emphasizes the relevance of dermal absorption of the aromatic amine ortho-toluidine considering four workers with different skin status (healthy, erythematous and burned skin as well as dishydrotic eczema) during the vulcanisation process of rubber products in a components supplier plant for automobile industry. The results of our case report show that dermal absorption of o-toluidine through damaged epidermal barrier is significantly higher than through healthy skin.

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Figures

Figure 1
Figure 1
Relationship between the concentration of o-toluidine in ambient air at the workplace and the relative internal exposure (RIE).
See this image and copyright information in PMC

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