doi: 10.1039/b605318a.
Epub 2006 Jun 14.
Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin
Affiliations
- PMID: 16855704
- DOI: 10.1039/b605318a
Item in Clipboard
Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin
Chem Commun (Camb).
.
Abstract
Heparin oligosaccharides derived by nitrous acid depolymerization of heparin have been immobilized on amine-coated glass slides. The formation of a Schiff base creates heparin chips that are a suitable platform for the high-throughput analysis of carbohydrate-protein interactions.
Similar articles
-
Conformational flexibility of a synthetic glycosylaminoglycan bound to a fibroblast growth factor. FGF-1 recognizes both the (1)C(4) and (2)S(O) conformations of a bioactive heparin-like hexasaccharide.J Am Chem Soc. 2005 Apr 27;127(16):5778-9. doi: 10.1021/ja043363y. J Am Chem Soc. 2005. PMID: 15839662
-
Microarrays of synthetic heparin oligosaccharides.J Am Chem Soc. 2006 Mar 8;128(9):2766-7. doi: 10.1021/ja057584v. J Am Chem Soc. 2006. PMID: 16506732
-
Preparation and use of microarrays containing synthetic heparin oligosaccharides for the rapid analysis of heparin-protein interactions.Chemistry. 2006 Nov 24;12(34):8664-86. doi: 10.1002/chem.200601103. Chemistry. 2006. PMID: 17066397
-
Deciphering the glycosaminoglycan code with the help of microarrays.Mol Biosyst. 2008 Jul;4(7):707-11. doi: 10.1039/b802217h. Epub 2008 May 23. Mol Biosyst. 2008. PMID: 18563243 Review.
-
PI-88 and novel heparan sulfate mimetics inhibit angiogenesis.Semin Thromb Hemost. 2007 Jul;33(5):557-68. doi: 10.1055/s-2007-982088. Semin Thromb Hemost. 2007. PMID: 17629854 Review.
Cited by
-
Chemoenzymatic synthesis of glycosaminoglycans: re-creating, re-modeling and re-designing nature's longest or most complex carbohydrate chains.Glycobiology. 2013 Jul;23(7):764-77. doi: 10.1093/glycob/cwt016. Epub 2013 Mar 11. Glycobiology. 2013. PMID: 23481097 Free PMC article. Review.
-
A versatile salt-based method to immobilize glycosaminoglycans and create growth factor gradients.Glycoconj J. 2019 Jun;36(3):227-236. doi: 10.1007/s10719-019-09872-4. Epub 2019 May 4. Glycoconj J. 2019. PMID: 31055697 Free PMC article.
-
Signal amplification of target protein on heparin glycan microarray.Anal Biochem. 2008 Dec 1;383(1):116-21. doi: 10.1016/j.ab.2008.07.037. Epub 2008 Aug 6. Anal Biochem. 2008. PMID: 18722996 Free PMC article.
-
Carbohydrate microarrays.Chem Soc Rev. 2013 May 21;42(10):4310-26. doi: 10.1039/c2cs35401b. Epub 2012 Nov 28. Chem Soc Rev. 2013. PMID: 23192235 Free PMC article. Review.
-
Heparan sulfate proteoglycans present PCSK9 to the LDL receptor.Nat Commun. 2017 Sep 11;8(1):503. doi: 10.1038/s41467-017-00568-7. Nat Commun. 2017. PMID: 28894089 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
