Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Jul 1;40(13):4055-65.
doi: 10.1021/es0630184.

Toxicogenomics in regulatory ecotoxicology

Gerald T Ankley  1 , George P Daston, Sigmund J Degitz, Nancy D Denslow, Robert A Hoke, Sean W Kennedy, Ann L Miracle, Edward J Perkins, Jason Snape, Donald E Tillitt, Charles R Tyler, Donald Versteeg
Affiliations

Toxicogenomics in regulatory ecotoxicology

Gerald T Ankley et al. Environ Sci Technol. .
No abstract available

PubMed Disclaimer

Figures

FIGURE 1
FIGURE 1
Increase in research activity in genomics and toxicogenomics over the past decade
FIGURE 2
FIGURE 2
How toxicogenomic data could be incorporated into a generic tiered testing framework for prospective ecological risk assessments
FIGURE 3
FIGURE 3
Where toxicogenomic data could be incorporated into a generic tiered testing framework for diagnostic ecological risk assessments
FIGURE 4
FIGURE 4
Conceptual timeline and relative resource requirements for the development and integration of toxicogenomic data into regulatory programs
See this image and copyright information in PMC

References

    1. Nuwaysir EF, et al. Microarrays and Toxicology: The Advent of Toxicogenomics. Mol Carcinogen. 1999;24:153–159. - PubMed
    1. MacGregor JT. The Future of Regulatory Toxicology: Impact of the Biotechnology Revolution. Toxicol Sci. 2003;75:236–248. - PubMed
    1. Waters MD, Fostel JM. Toxicogenomics and Systems Toxicology: Aims and Prospects. Nat Rev Genet. 2004;5:936–948. - PubMed
    1. Bilello JA. The Agony and Ecstasy of “OMIC” Technologies in Drug Development. Curr Mol Med. 2005;5:39–52. - PubMed
    1. Lühe A, et al. Toxicogenomics in the Pharmaceutical Industry: Hollow Promises or Real Benefit? Mutat Res. 2005;575:102–115. - PubMed

Publication types