Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006;34(4):313-7.
doi: 10.1515/JPM.2006.060.

Pleural fluid/serum immunoglobulin ratio is a diagnostic marker for congenital chylothorax in utero

Kiyomi Tsukimori  1 , Naoyuki Nakanami, Kotaro Fukushima, Takazumi Yoshimura, Shunji Hikino, Hitoo Nakano
Affiliations

Pleural fluid/serum immunoglobulin ratio is a diagnostic marker for congenital chylothorax in utero

Kiyomi Tsukimori et al. J Perinat Med. 2006.

Abstract

Objective: To distinguish congenital chylothorax from other causes of hydrothorax in utero.

Methods: Serum and pleural fluid samples from 8 fetuses with congenital chylothorax and 5 control fetuses with other causes of hydrothorax were tested for total protein, albumin, IgG, IgA, and IgM.

Results: Fetuses with congenital chylothorax had higher levels of IgG in pleural fluid, but not the other four proteins, than control fetuses (P<0.05). There were no significant differences in serum proteins among fetuses. When we examined pleural fluid to serum ratios, the IgG ratio in fetuses with congenital chylothorax was significantly higher than that of control fetuses (P<0.05). The IgG ratio in chylothorax was greater than 0.6 regardless of lymphocyte count.

Conclusion: Pleural fluid/serum IgG ratio may be a diagnostic marker for congenital chylothorax in utero.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources