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. 2006 Aug;23(8):650-3.
doi: 10.1136/emj.2005.033993.

Identifying barriers to prehospital thrombolysis in the treatment of acute myocardial infarction

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Identifying barriers to prehospital thrombolysis in the treatment of acute myocardial infarction

T C Hanson et al. Emerg Med J. 2006 Aug.

Abstract

Background and objectives: After an acute myocardial infarction (AMI) prehospital thrombolysis (PHT) reduces mortality compared with inhospital thrombolysis. In practice, a relatively small proportion of the total population with AMI receives PHT. This study was designed to identify the current barriers to PHT.

Methods: A retrospective practice review of 57 consecutive patients treated in or before arrival at a district general hospital emergency department. All patients received thrombolysis for an AMI.

Results: The main barriers to delivery of PHT appear to be the inclusion and exclusion criteria laid out in the ambulance service central guidelines. Despite recent widening of the inclusion criteria, 54% of patients eligible for immediate treatment on arrival in hospital either received or were eligible for PHT.

Conclusion: To increase the number of patients who are eligible for PHT these guidelines need to be revised further in line with inhospital criteria for thrombolysis.

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Conflict of interest statement

Competing interests: none declared

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References

    1. Van de Werf F, Ardissino D, Betriu A.et al Management of acute myocardial infarction in patients presenting with ST‐segment elevation. The Task Force on the Management of Acute Myocardial Infarction of the European Society of Cardiology. Eur Heart J 20032428–66. - PubMed
    1. Boersma E, Maas A C P, Deckers J W.et al Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour. Lancet 1996348771–775. - PubMed
    1. [No authors listed] Reperfusion in acute myocardial infarction. Drug Ther Bull 20054349–53. - PubMed
    1. Kendall J M, McCabe S E. The use of audit to set up a thrombolysis programme in the accident and emergency department. J Accid Emerg Med 19961349–53. - PMC - PubMed
    1. [No authors listed] The pre‐hospital management of acute heart attacks. Recommendations of a Task Force of the European Society of Cardiology and the European Resuscitation Council. Eur Heart J 1998191140–1164. - PubMed