Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 Aug;7(8):628-43.
doi: 10.1038/nrn1955.

Therapeutic interventions after spinal cord injury

Sandrine Thuret  1 , Lawrence D F Moon, Fred H Gage
Affiliations
Review

Therapeutic interventions after spinal cord injury

Sandrine Thuret et al. Nat Rev Neurosci. 2006 Aug.

Erratum in

  • Nat Rev Neurosci. 2006 Nov;7(11):902

Abstract

Spinal cord injury (SCI) can lead to paraplegia or quadriplegia. Although there are no fully restorative treatments for SCI, various rehabilitative, cellular and molecular therapies have been tested in animal models. Many of these have reached, or are approaching, clinical trials. Here, we review these potential therapies, with an emphasis on the need for reproducible evidence of safety and efficacy. Individual therapies are unlikely to provide a panacea. Rather, we predict that combinations of strategies will lead to improvements in outcome after SCI. Basic scientific research should provide a rational basis for tailoring specific combinations of clinical therapies to different types of SCI.

PubMed Disclaimer

MeSH terms