Ontogeny of corticotropin releasing hormone gene expression in rat hypothalamus--comparison with somatostatin
- PMID: 1685845
- DOI: 10.1016/0736-5748(91)90033-i
Ontogeny of corticotropin releasing hormone gene expression in rat hypothalamus--comparison with somatostatin
Abstract
Using in situ hybridization histochemistry, corticotropin-releasing hormone gene expression is first detectable in the parvocellular portion of the rat paraventricular nucleus on the 17th fetal day. The prevalence of messenger RNA for corticotropin releasing hormone decreases perinatally, specifically between the 19th and 21st fetal days. By the 4th postnatal day, CRH gene expression is similar to that of the adult rat. Somatostatin messenger-RNA is detectable on the 14th fetal day in the periventricular nucleus. No perinatal hiatus in somatostatin gene expression is evident.
Similar articles
-
Ontogeny of somatostatin gene expression in rat diencephalon.Dev Neurosci. 1991;13(3):176-80. doi: 10.1159/000112155. Dev Neurosci. 1991. PMID: 1684321
-
Developmental expression of corticotropin releasing hormone messenger RNA and peptide in rat hypothalamus.Peptides. 1989 Nov-Dec;10(6):1165-9. doi: 10.1016/0196-9781(89)90009-0. Peptides. 1989. PMID: 2576125
-
Ontogeny of thyrotropin-releasing hormone gene expression in the rat diencephalon.Neuroendocrinology. 1989 Jun;49(6):631-40. doi: 10.1159/000125180. Neuroendocrinology. 1989. PMID: 2505155
-
Regulation of gene expression in the hypothalamus: hybridization histochemical studies.Ciba Found Symp. 1992;168:127-38; discussion 138-43. Ciba Found Symp. 1992. PMID: 1425021 Review.
-
Neuroendocrine gene expression in the hypothalamus: in situ hybridization histochemical studies.Cell Mol Neurobiol. 1987 Dec;7(4):353-66. doi: 10.1007/BF00733788. Cell Mol Neurobiol. 1987. PMID: 2897879 Free PMC article. Review.
Cited by
-
A Randomized Controlled Trial on the Study of Effectiveness and Safety of Hormonal (ACTH) Treatment Alone versus Hormonal (ACTH) with Levetiracetam for Epileptic Spasms.J Neurosci Rural Pract. 2022 Jun 8;13(3):403-410. doi: 10.1055/s-0042-1744469. eCollection 2022 Jul. J Neurosci Rural Pract. 2022. PMID: 35946019 Free PMC article.
-
Abnormal dendritic maturation of developing cortical neurons exposed to corticotropin releasing hormone (CRH): Insights into effects of prenatal adversity?PLoS One. 2017 Jun 28;12(6):e0180311. doi: 10.1371/journal.pone.0180311. eCollection 2017. PLoS One. 2017. PMID: 28658297 Free PMC article.
-
Glucocorticoid receptor mRNA ontogeny in the fetal and postnatal rat forebrain.Mol Cell Neurosci. 1994 Oct;5(5):385-93. doi: 10.1006/mcne.1994.1048. Mol Cell Neurosci. 1994. PMID: 7820362 Free PMC article.
-
Differential regulation of the expression of corticotropin-releasing factor receptor type 2 (CRF2) in hypothalamus and amygdala of the immature rat by sensory input and food intake.J Neurosci. 1999 May 15;19(10):3982-91. doi: 10.1523/JNEUROSCI.19-10-03982.1999. J Neurosci. 1999. PMID: 10234028 Free PMC article.
-
Corticotropin-releasing hormone mediates the response to cold stress in the neonatal rat without compensatory enhancement of the peptide's gene expression.Endocrinology. 1994 Dec;135(6):2364-8. doi: 10.1210/endo.135.6.7988418. Endocrinology. 1994. PMID: 7988418 Free PMC article.