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Comment
. 2006 Jul 25;16(14):R540-2.
doi: 10.1016/j.cub.2006.06.038.

Cell cycle: sustained ERK signalling represses the inhibitors

Andrew D Sharrocks  1
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Cell cycle: sustained ERK signalling represses the inhibitors

Andrew D Sharrocks. Curr Biol. .
Free article

Abstract

The duration of ERK pathway signalling determines the proliferative response of cells. A recent study has shown that cell cycle re-entry requires the downregulation of an anti-proliferative gene cluster following sustained activation of the ERK pathway.

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