Comment
doi: 10.1016/j.cub.2006.06.038.
Cell cycle: sustained ERK signalling represses the inhibitors
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- PMID: 16860730
- DOI: 10.1016/j.cub.2006.06.038
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Comment
Cell cycle: sustained ERK signalling represses the inhibitors
Curr Biol.
.
Free article
Abstract
The duration of ERK pathway signalling determines the proliferative response of cells. A recent study has shown that cell cycle re-entry requires the downregulation of an anti-proliferative gene cluster following sustained activation of the ERK pathway.
Comment on
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Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression.Curr Biol. 2006 Jun 20;16(12):1171-82. doi: 10.1016/j.cub.2006.04.044. Curr Biol. 2006. PMID: 16782007
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