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Comment
. 2006 Jul;25(1):11-3.
doi: 10.1016/j.immuni.2006.07.005.

Signaling in the immunological synapse: defining the optimal size

Abraham Kupfer  1
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Comment

Signaling in the immunological synapse: defining the optimal size

Abraham Kupfer. Immunity. 2006 Jul.
Free article

Abstract

In this issue of Immunity, Varma et al. (2006) report that in the synapses between T cells and planar bilayers, T cell receptor (TCR) proximal signaling takes place in peripheral TCR-microclusters that form continually and that TCR signaling ceases when they fuse with the central supramolecular activation cluster.

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