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Review
. 1991 Nov;12(11):392-5.
doi: 10.1016/0167-5699(91)90137-I.

Functional subsets of allergen-reactive human CD4+ T cells

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Review

Functional subsets of allergen-reactive human CD4+ T cells

M L Kapsenberg et al. Immunol Today. 1991 Nov.

Abstract

After a period of resistance, the concept of human helper T (TH)-cell subsets is gaining currency. This is the result of analyses from a number of laboratories on the cytokine profiles of T-cell clones prepared from chronically-infected and hypersensitive individuals. Here, Martien Kapsenberg and colleagues summarize these studies and speculate on the significance of skewed TH1 and TH2 responses.

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