Minimally invasive endoscopic resection of sinonasal malignancies and skull base surgery

Abstract

Conclusions: Sinonasal malignancies without far lateral extension, intracranial invasion or orbital infiltration can be safely excised and reconstructed endoscopically with a satisfactory outcome.

Objectives: To evaluate the safety and efficacy of strictly endoscopic resection of malignant sinonasal neoplasms.

Patients and methods: Seven patients with sinonasal malignancies had received a minimally invasive endoscopic resection. Among them, two cases invaded the skull base. All patients were operated with curative intent.

Results: All the tumors were removed successfully by strictly endoscopic surgery. Two patients who had invasion of the skull base (28.6%) accepted postoperative radiotherapy. No complications associated with the operation occurred. The patients were followed up for 15-57 months (average 36.4 months). No local recurrence was noted in this series to date. The disease-free survival rate was 100% at a mean follow-up duration of 36.4 months.