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Clinical Trial
. 2006 Jul 21;12(27):4411-5.
doi: 10.3748/wjg.v12.i27.4411.

Endoscopic scoring of late gastrointestinal mucosal damage after adjuvant radiochemotherapy

Resat Dabak  1 , Oya Uygur-Bayramicli, Cengiz Gemici, Dilek Yavuzer, Mehmet Sargin, Mehmet Yildirim
Affiliations
Clinical Trial

Endoscopic scoring of late gastrointestinal mucosal damage after adjuvant radiochemotherapy

Resat Dabak et al. World J Gastroenterol. .

Abstract

Aim: To evaluate late effects of chemoradiation on gastrointestinal mucosa with an endoscopic scoring system and compare it to a clinical scoring system.

Methods: Twenty-four patients going to receive chemoradiation after gastric surgery underwent endoscopy four wk after surgery and one year after the chemoradiation finished. Upper gastrointestinal findings were recorded according to a system proposed by World Organisation for Digestive Endoscopy (OMED) and clinical scoring was done with RTOG-EORTC radiation morbidity scoring systems.

Results: There was no significant endoscopic difference in gastric and intestinal mucosa after chemoradiation (P > 0.05) and there was no association between endoscopic scores and clinical scores. Endoscopic changes were minimal.

Conclusion: Late effects after chemoradiation in operated patients with gastric cancers can be evaluated with an endoscopic scoring system objectively and this system is superior to clinical scoring systems.

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