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. 2006 Aug 1;20(12):1673-5.
doi: 10.1097/01.aids.0000238417.05819.40.

DEFB1 gene polymorphisms and increased risk of HIV-1 infection in Brazilian children

Michele Milanese  1 , Ludovica Segat, Alessandra Pontillo, Luiz Claudio Arraes, José Luiz de Lima Filho, Sergio Crovella
Affiliations

DEFB1 gene polymorphisms and increased risk of HIV-1 infection in Brazilian children

Michele Milanese et al. AIDS. .

Abstract

In our study we analysed three single nucleotide polymorphisms (SNPs) in the 5' untranslated region (UTR) of the DEFB1 gene, namely -52(G/A) -44(C/G) and -20(G/A), in three groups of northeastern Brazilian children in order to assess their role in HIV-1 infection. Our results allowed us to hypothesize that the SNPs located in the 5' UTR of the DEFB1 gene can be employed as a marker of risk for HIV-1 infection.

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