doi: 10.1021/ol061133d.
Highly enantioselective synthesis of beta-amino alcohols
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- PMID: 16869647
- DOI: 10.1021/ol061133d
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Highly enantioselective synthesis of beta-amino alcohols
Org Lett.
.
Abstract
[reaction: see text] N,N-Dialkyl-beta-amino alcohols derived from alpha-amino acids can be rearranged enantiospecifically by using TFAA/Et3N/NaOH to give 1,2-amino alcohols with enantiomeric excess up to 99%.
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