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Comparative Study
. 2006 Aug;50(8):2872-4.
doi: 10.1128/AAC.01647-05.

qnr prevalence in ceftazidime-resistant Enterobacteriaceae isolates from the United States

A Robicsek  1 , J Strahilevitz, D F Sahm, G A Jacoby, D C Hooper
Affiliations
Comparative Study

qnr prevalence in ceftazidime-resistant Enterobacteriaceae isolates from the United States

A Robicsek et al. Antimicrob Agents Chemother. 2006 Aug.

Abstract

We screened 313 ceftazidime-resistant Enterobacteriaceae isolates obtained in the United States from 1999 to 2004 for all three known qnr genes. A qnr gene was present in 20% of Klebsiella pneumoniae isolates, 31% of Enterobacter sp. isolates, and 4% of Escherichia coli isolates. qnrA and qnrB occurred with equivalent frequencies and, except for qnrB in enterobacters, were stable over time. qnrS was absent.

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Figures

FIG. 1.
FIG. 1.
Amino acid sequence alignment of qnrB variants. qnrB5 was recently identified in Salmonella enterica serotype Berta isolates from the United States.
See this image and copyright information in PMC

References

    1. Clinical and Laboratory Standards Institute. 2005. Performance standards for antimicrobial susceptibility testing, 15th informational supplement. Clinical and Laboratory Standards Institute, Wayne, Pa.
    1. Gay, K., A. Robicsek, J. Strahilevitz, C. H. Park, G. A. Jacoby, T. J. Barrett, F. Medalla, T. M. Chiller, and D. C. Hooper. Plasmid mediated quinolone resistance in non-Typhi serotypes of Salmonella enterica. Clin. Infect. Dis., in press. - PubMed
    1. Hata, M., M. Suzuki, M. Matsumoto, M. Takahashi, K. Sato, S. Ibe, and K. Sakae. 2005. Cloning of a novel gene for quinolone resistance from a transferable plasmid in Shigella flexneri 2b. Antimicrob. Agents Chemother. 49:801-803. - PMC - PubMed
    1. Jacoby, G. A., K. E. Walsh, D. M. Mills, V. J. Walker, H. Oh, A. Robicsek, and D. C. Hooper. 2006. qnrB, another plasmid-mediated gene for quinolone resistance. Antimicrob. Agents Chemother. 50:1178-1182. - PMC - PubMed
    1. Martinez-Martinez, L., A. Pascual, and G. A. Jacoby. 1998. Quinolone resistance from a transferable plasmid. Lancet 351:797-799. - PubMed

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