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. 2006 Aug;50(8):2880-2.
doi: 10.1128/AAC.00186-06.

First detection of the plasmid-mediated class A carbapenemase KPC-2 in clinical isolates of Klebsiella pneumoniae from South America

Maria Virginia Villegas  1 , Karen Lolans, Adriana Correa, Carlos Jose Suarez, Jaime A Lopez, Marta Vallejo, John P Quinn; Colombian Nosocomial Resistance Study Group
Affiliations

First detection of the plasmid-mediated class A carbapenemase KPC-2 in clinical isolates of Klebsiella pneumoniae from South America

Maria Virginia Villegas et al. Antimicrob Agents Chemother. 2006 Aug.

Abstract

The plasmid-mediated class A carbapenemase KPC-2 was isolated from unrelated Klebsiella pneumoniae isolates in Medellin, Colombia. These KPC enzymes are the first from South America and the second isolation outside of the United States. The expanding geographic spread of KPC carbapenemases underscores the importance of clinical recognition of these enzymes.

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Figures

FIG. 1.
FIG. 1.
Schematic representation (not to scale) of the cloned plasmid 4.67-kb BamHI insert from KPN2303. Open reading frames and transcriptional orientation are represented by arrows. GenBank sequences listed below ORFs represent those with the most significant similarity. The dashed line represents the upstream portion of AF481906 not included in our cloned fragment.
See this image and copyright information in PMC

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