Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975 Apr;78(4):664-74.
doi: 10.1530/acta.0.0780664.

The specificity and application of a radioimmunoassay for the alpha-subunit of luteinizing hormone in man

C Hagen, A S McNeilly

The specificity and application of a radioimmunoassay for the alpha-subunit of luteinizing hormone in man

C Hagen et al. Acta Endocrinol (Copenh). 1975 Apr.

Abstract

A sensitive radioimmunoassay for the alpha-subunit of LH has been developed. Differences in the immunopotency of LH, FSH, and subunit preparations were found and are described in detail. The assay has been applied to the measurement of circulating levels of alpha-subunit; higher levels of alpha-subunit were found in post-menopausal than in pre-menopausal women, or men, and a rise in alpha-subunit was seen after LH-RH but not TRH administration. Elevated levels of free alpha-subunit were found in foetal cord blood at term. These results suggest that the alpha-subunit circulates independently of the intact pituitary and placental glycoprotein hormones.

PubMed Disclaimer

MeSH terms