Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Dec;35(12):2639-42.
doi: 10.1128/AAC.35.12.2639.

Inhibition of membrane potential-dependent amino acid transport by daptomycin

N E Allen  1 , W E Alborn Jr, J N Hobbs Jr
Affiliations

Inhibition of membrane potential-dependent amino acid transport by daptomycin

N E Allen et al. Antimicrob Agents Chemother. 1991 Dec.

Abstract

Daptomycin inhibits the formation of UDP-N-acetylmuramyl-pentapeptide in Bacillus megaterium by inhibiting active transport of amino acids incorporated into the pentapeptide. The ability of daptomycin to inhibit active transport and peptidoglycan formation may be due to its ability to disrupt the transmembrane electrochemical gradient.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Biochemistry. 1977 Mar 8;16(5):854-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1982 Nov;79(21):6693-7 - PubMed
    1. Ann N Y Acad Sci. 1974 May 10;235(0):364-86 - PubMed
    1. Antonie Van Leeuwenhoek. 1971;37(4):537-52 - PubMed
    1. J Bacteriol. 1970 Nov;104(2):808-13 - PubMed

MeSH terms