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. 2006 Aug;29(8):1794-9.
doi: 10.2337/dc06-0506.

Cognitive dysfunction is associated with poor diabetes control in older adults

Medha Munshi  1 , Laura Grande, Mellody Hayes, Darlene Ayres, Emmy Suhl, Roberta Capelson, Susan Lin, William Milberg, Katie Weinger
Affiliations

Cognitive dysfunction is associated with poor diabetes control in older adults

Medha Munshi et al. Diabetes Care. 2006 Aug.

Abstract

Objective: To evaluate the association between cognitive dysfunction and other barriers and glycemic control in older adults with diabetes.

Research design and methods: Patients over the age of 70 years presenting to a geriatric diabetes clinic were evaluated for barriers to successful diabetes management. Patients were screened for cognitive dysfunction with the Mini Mental State Examination (MMSE) and a clock-drawing test (CDT) scored by 1) a method validated by Mendez et al. and 2) a modified CDT (clock in a box [CIB]). Depression was evaluated with the Geriatric Depression Scale. Interview questionnaires surveyed activities of daily living (ADLs) and instrumental ADLs (IADLs), as well as other functional disabilities.

Results: Sixty patients (age 79 +/- 5 years, diabetes duration 14 +/- 13 years) were evaluated. Thirty-four percent of patients had low CIB (< or =5), and 38% of patients had low CDT (< or =13). Both CIB as well as CDT were inversely correlated with HbA(1c), suggesting that cognitive dysfunction is associated with poor glycemic control (r = -0.37, P < 0.004 and r = -0.38, P < 0.004, respectively). Thirty-three percent of patients had depressive symptoms with greater difficulty completing the tasks of the IADL survey (5.7 +/- 1.7 vs. 4.6 +/- 2.0; P < 0.03). These older adults with diabetes had a high incidence of functional disabilities, including hearing impairment (48%), vision impairment (53%), history of recent falls (33%), fear of falls (44%), and difficulty performing IADLs (39%).

Conclusions: Older adults with diabetes have a high risk of undiagnosed cognitive dysfunction, depression, and functional disabilities. Cognitive dysfunction in this population is associated with poor diabetes control.

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Figures

Figure 1
Figure 1
Patients with cognitive dysfunction (CIB ≤5 or CDT ≤13) had a higher A1C, indicating poorer glycemic control compared with patients without cognitive dysfunction (P < 0.003 with CIB and P < 0.05 with CDT).□, CIB; ■, CDT.
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