Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2006 Jul 28;12(28):4586-7.
doi: 10.3748/wjg.v12.i28.4586.

Diagnosis of autoimmune gastritis by high resolution magnification endoscopy

George-K Anagnostopoulos  1 , Krish Ragunath, Anthony Shonde, Christopher J Hawkey, Kenshi Yao
Affiliations
Case Reports

Diagnosis of autoimmune gastritis by high resolution magnification endoscopy

George-K Anagnostopoulos et al. World J Gastroenterol. .

Abstract

Endoscopic visualisation of gastric atrophy is usually not feasible with conventional endoscopy. Magnifying endoscopy is helpful to analyze the subepithelial microvascular architecture as well as the mucosal surface microstructure without tissue biopsy. Using this technique we were able to describe the normal gastric microvasculature pattern and we also identified characteristic patterns in two cases of autoimmune atrophic gastritis.

PubMed Disclaimer

Figures

Figure 1
Figure 1
A: Magnified view of gastric antral mucosa in our patient. All parts of the antral mucosa demonstrated a coil-shaped subepithelial capillary network (SECN) in regular arrangement; B: Magnified endoscopic view of the gastric body mucosa in our patient. Loss of the normal SECN and collecting venules (arrows) in irregular shape and arrangement were evident. These findings are compatible with those of gastric atrophy; C: Histology reveales decreased density of glands, loss of specialised glands in the gastric body; D: Magnified view of normal gastric body mucosa in another healthy patient Honeycomb-like SECN with collecting venules in regular arrangement can be seen clearly.
See this image and copyright information in PMC

References

    1. Redéen S, Petersson F, Jönsson KA, Borch K. Relationship of gastroscopic features to histological findings in gastritis and Helicobacter pylori infection in a general population sample. Endoscopy. 2003;35:946–950. - PubMed
    1. Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994. Am J Surg Pathol. 1996;20:1161–1181. - PubMed
    1. Bruno MJ. Magnification endoscopy, high resolution endoscopy, and chromoscopy; towards a better optical diagnosis. Gut. 2003;52 Suppl 4:iv7–i11. - PMC - PubMed
    1. Kapadia CR. Gastric atrophy, metaplasia, and dysplasia: a clinical perspective. J Clin Gastroenterol. 2003;36:S29–36; discussion S61-62. - PubMed
    1. Yao K, Oishi T, Matsui T, Yao T, Iwashita A. Novel magnified endoscopic findings of microvascular architecture in intramucosal gastric cancer. Gastrointest Endosc. 2002;56:279–284. - PubMed

Publication types