[Present opinions on treatment of nasal polyps]

Abstract

Nasal polyps concern about 1-4% population however the cause of disease does not be well-known. With this reason there have not causal treatment of the disease. The aim of nasal polyps treatment is as follows: removal or decrease the polyps' mass, improvement of patency of the nose, improvement of smell, opening the passage of paranasal sinuses, decrease the inflammatory discharge from the paranasal sinuses, prevention the recurrences the disease as well as improvement of quality of life. In the treatment of nasal polyps surgery, pharmacological treatment and combined both these methods were performed. The surgical treatment is not only removal of nasal polyps, but also to try to correct anatomical abnormalities. The introduction of endoscopic surgery, computer assisted navigation and microdebriders made possible to very precise surgical management of the nose and paranasal sinuses and decrease the number of complications. Surgery treatment of the nasal polyps is necessary in every suspicious about neoplasmic change case because material lets us to histopathologic examination. Pharmacological treatment of nasal polyps contains many groups of medicines. These medicines show anti-inflammatory and anti-swelling effects. Pharmacological treatment of nasal polyps can be conducted as a primary procedure and more often as a post surgery treatment. The following groups of medicines are used in pharmacological treatment of nasal polyps: glucocorticosteroids, antibiotics, antifungal, anti-leukotrienes, capsaicin, antihistaminic, lysine of acetylsalicylic acid, furosemid and antibody against IL-5. The use of glucorticosteroids in long treatment after surgical operation increased the time of remission of disease. Also in well-chosen cases use of another medicines permits on extension the time of remission and decrease a dose of used glucocorticosteroids.